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hdac inhibitor vorinostat  (TargetMol)


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    TargetMol hdac inhibitor vorinostat
    Hdac Inhibitor Vorinostat, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hdac+inhibitor+vorinostat/Vorinostat/pm41946423-63-30-33
    Average 94 stars, based on 10 article reviews
    hdac inhibitor vorinostat - by Bioz Stars, 2026-09
    94/100 stars

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    Irradiation:

    Article Title: Alternative End-Joining Dependency Imposed by miR-21-5p Defines Radiation Resistance and a Targetable Vulnerability in Oral Squamous Cell Carcinoma.
    Article Snippet: Please cite this article as: Lin Ma PhD , Nilupaier Tayier MPhil , Weitao Hu MD , Junyang Chen MPhil , Lu Wen BS , Yanhe Li BS , Xiaoran Shi MPhil , Baoxu Li MPhil , Yonghui Luo BS , Yongqiang Deng MD , Xinghan Li MD , Qi Liu PhD , Alternative End-Joining Dependency Imposed by miR-21-5p Defines Radiation Resistance and a Targetable Vulnerability in Oral Squamous Cell Carcinoma, International Journal of Radiation Oncology, Biology, Physics (2026), doi: https://doi.org/10.1016/j.ijrobp.2026.03.037



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    Image Search Results


    Inhibitory effects of HDAC inhibitors vorinostat and entinostat. A and B , Swarm plots with histogram bars (mean ± SD) and ( C ) representative microscopic pictures of Vimentin-stained G55T2 xenograft tissue slice tandem cocultures (XTCCs) treated with 1% DMSO or different concentrations of Vorinostat and Entinostat (7 days of total XTCC cultivation). Results are from at least two biological replicates with 6 to 22 technical replicates. Unpaired t test with Welch's correction, ns = not significant. Asterisks indicate statistically significant differences (∗, p < 0.05; ∗∗, p < 0.01; ∗∗∗, p < 0.001 and ∗∗∗∗, p < 0.0001). XTCC, xenograft tissue slice tandem co-culture.

    Journal: The Journal of Biological Chemistry

    Article Title: Xenograft tissue slice tandem co-cultures are a highly specific model to selectively analyze drug inhibitory effects on glioblastoma invasion

    doi: 10.1016/j.jbc.2025.110986

    Figure Lengend Snippet: Inhibitory effects of HDAC inhibitors vorinostat and entinostat. A and B , Swarm plots with histogram bars (mean ± SD) and ( C ) representative microscopic pictures of Vimentin-stained G55T2 xenograft tissue slice tandem cocultures (XTCCs) treated with 1% DMSO or different concentrations of Vorinostat and Entinostat (7 days of total XTCC cultivation). Results are from at least two biological replicates with 6 to 22 technical replicates. Unpaired t test with Welch's correction, ns = not significant. Asterisks indicate statistically significant differences (∗, p < 0.05; ∗∗, p < 0.01; ∗∗∗, p < 0.001 and ∗∗∗∗, p < 0.0001). XTCC, xenograft tissue slice tandem co-culture.

    Article Snippet: The pharmacological agents used in this work comprise the oral alkylating drug Temozolomide (TMZ; Sigma Aldrich Co, St Louis, USA), the two HDAC inhibitors Vorinostat and Entinostat (both from MedChemExpress, Monmouth Junction, NJ, USA), and the neurotoxic peptide Apamin (Apa; Sigma-Aldrich Chemie).

    Techniques: Staining, Co-Culture Assay